The “surgery” mentioned in this article refers to brain pacemaker surgery, also known as deep brain electrical stimulation therapy, or DBS, which is the second milestone in the treatment of Parkinson’s disease after levodopa. The procedure was introduced to China at the end of 1990s, and the Department of Functional Neurosurgery of Tangdu Hospital of Air Force Military Medical University has been carrying out this technology since 1999, and is one of the first centers in China to carry out this technology. With the advantages of low surgical risk, minimally invasive, adjustable, reversible and less complications, pacemaker therapy has been recognized and favored by more and more multifunctional neurosurgeons and neurologists in the treatment of functional brain diseases, and more and more patients with Parkinson’s disease are treated with pacemaker therapy. Since Parkinson’s disease symptoms are complex and diverse and easily misdiagnosed, a clear diagnosis is the first important factor for successful surgery with good outcomes. Firstly, primary Parkinson’s disease is a good indication for surgery, and the postoperative effect is immediate. Secondly, the surgery requires fine and precise intraoperative operation by the surgeon, and the electrodes must be precisely implanted into the target target points deep in the brain, and the ring must be interlocked in order to play a therapeutic role, which requires the surgeon to have solid and profound knowledge of neuroanatomy and electrophysiology, superb surgical operation technique and good response to various accidents Psychological quality. For patients with Parkinson’s disease who choose surgery, there is also the issue of the time window for surgery, i.e., when to have surgery to maximize the desired effect. Parkinson’s disease is a chronic progressive disease, and the timing of surgery is particularly important. With timely intervention, you can buy yourself 20 or 30 wonderful years. Data published in the New England Journal, the world’s leading medical journal, shows that Parkinson’s patients treated early with surgical pacemaker implantation have very significant improvements in both quality of life and motor skills, which in turn also greatly reduces drug-induced motor complications. Age and disease duration are important factors in the choice between pharmacological or surgical treatment. Younger patients with more improvement in quality of life and rigidity symptoms, fewer cognitive complications and a slower deterioration of medial symptoms, presenting with drug efficacy that has significantly decreased or with severe motor fluctuations or isokinetic disorders, are the best time to consider undergoing pacemaker implantation. About a month after the pacemaker surgery, once some interfering factors have been removed, the patient needs to come to the hospital for the first start-up. The doctor will set and adjust multiple sets of parameters such as voltage and frequency according to the patient’s specific situation and daily living habits, so that the patient can achieve the best treatment effect. Since Parkinson’s disease is a progressive disease, the doctor will also manage the patient for a long time after the surgery as the disease progresses and the patient’s symptoms change. Parkinson’s disease is not terrible, and modern medicine is constantly advancing. Through reasonable medication, timely surgery, and persistent exercise, patients’ quality of life can be greatly improved, allowing Parkinson’s disease patients to live a life close to normal and reducing the burden on their families and society. With the active exploration and efforts of functional neurosurgery experts, the surgery has become safer and the efficacy more and more durable. We hope that patients with Parkinson’s disease can have a scientific and positive attitude, cooperate with doctors, work together, face Parkinson’s disease bravely, and light up the light of life again!