Chinese medicine is unique in its holistic view and evidence-based treatment, while the combination of Chinese and Western medicine combines disease identification with evidence identification, local treatment with overall treatment, anti-cancer with corrective treatment, and medical treatment with health care. The purpose of comprehensive tumor treatment is to maximize the clinical cure rate of tumor and the survival quality of patients. Chinese medicine is good at supporting the righteousness and strengthening the root, which can enhance the immune function and anti-cancer ability of patients and regulate the imbalance of yin and yang and internal organs of patients, but its tumor suppressing effect is slower and weaker; while western medicine treatment methods, such as surgery, radiotherapy and chemotherapy, have stronger anti-cancer effect but have greater toxic side effects on the body. If we give full play to the respective strengths of Chinese medicine and Western medicine in treatment, complementing each other’s strengths and complementing each other’s weaknesses, the therapeutic effect will be better than that of purely Chinese medicine or Western medicine, which has been proved in clinical practice. ③ Combination of Chinese and Western medicine can enhance the immune function of tumor patients, reduce recurrence and metastasis, and improve the quality of survival and long-term efficacy; ④ Certain anti-cancer Chinese medicines can play a greater anti-cancer role through the combination with modern medical technology and methods. Combined Chinese and Western medicine treatment is a reasonable and effective comprehensive treatment plan formulated after the patient’s diagnosis. In order to “eliminate the evil without harming the righteousness”, effective modern medical treatments must be chosen according to the condition, while Chinese medicine treatment should be given according to the patient’s deficiency and reality. “If the patient is deficient, he or she should be treated with Chinese medicine. Of course, Chinese medicine treatment also has two categories: supporting the righteous and eliminating the evil. Eliminating the evil means anti-cancer treatment, including eliminating cancer foci by activating blood stasis, softening hardness and dissipating knots, clearing heat and detoxifying toxins, removing phlegm and dispelling dampness, opening meridians and activating channels, attacking toxins with toxins, etc. Meanwhile, comprehensive Chinese medicine treatment also includes single and experimental prescriptions, local treatment, acupuncture, qigong, food therapy and other methods. In conclusion, the clinical treatment of tumors by combining Chinese and Western medicine has summarized and figured out some rules and effective prescriptions, which has laid a good foundation for further in-depth research.