The most serious danger of gene mutation is to cause malignant solid tumors (e.g. lung cancer, intestinal cancer, etc.), hematologic malignant diseases (leukemia, myelodysplastic syndromes, myeloma, lymphoma, etc.), and other malignant diseases, and also has a certain relationship with the occurrence of some chronic diseases. Gene mutation refers to the genetic variations on chromosomes that can lead to loss of control of apoptosis and abnormal monoclonal proliferation when the human body is affected by environmental factors, harmful chemicals (benzene, formaldehyde, etc.), physical factors (X-rays, etc.), and chemotherapeutic drugs (alkylating agents, etc.), among many other undesirable factors. The monoclonal proliferation of abnormal cells in the body caused by gene mutation may lead to the occurrence of malignant solid tumors, hematologic malignant diseases and other diseases, which will seriously endanger the patient’s health, and even life-threatening, which is the most serious harm caused by gene mutation. In addition, hypertension, diabetes and other chronic diseases may also have gene mutations involved.