Usually, chronic sinusitis does not necessarily require long-term medication, and the exact duration of medication is determined by the individual’s condition, treatment plan, and treatment effect. At present, chronic sinusitis commonly used drugs are: 1. Glucocorticosteroids: glucocorticosteroids include oral and nasal two kinds of medication, nasal glucocorticosteroids course of treatment is generally recommended to be not less than 12 weeks, while oral glucocorticosteroids mainly due to individual condition there is a difference in the time of medication. 2. Macrolides: generally recommended long-term oral and not less than 12 weeks, such as erythromycin, azithromycin and so on. 3. Antibacterial drugs: antibacterial drugs take time due to the degree of infection, pathogenic bacteria, etc. There are large differences in the common amoxicillin, cephalosporin, etc.. 4. Antihistamines and anti-leukotriene drugs: the general taking time in 2-4 weeks, depending on the person. 5. Mucolytic and promotional agents: the main role of the drug is to promote the removal of nasal mucus, the specific taking time varies from person to person. Chronic sinusitis, should follow the doctor’s prescription medication.