Staying up late may lead to elevated aminotransferases. Staying up late for a long time can lead to mild elevation of aminotransferases, which can return to normal on its own after giving sufficient rest and restoring a normal routine, and sometimes it is not necessary to give clinical treatment. Chinese medicine believes that the best time for liver detoxification is between 11:00 pm and 3:00 am. If you are still not in sleep during this time, it will affect the normal function of the liver and cause toxic substances to accumulate in the liver, thus causing some damage to liver cells. In addition, staying up late for a long time will not only cause damage to the liver, but will also seriously affect the sleep pattern, causing symptoms of insomnia, and will have a certain impact on the cardiovascular and cerebrovascular. Not only can staying up late cause elevated aminotransferases, but also elevated aminotransferases can occur with long-term alcohol consumption, high-fat foods, strenuous exercise, or certain medications, but can return to normal after these triggers are removed. However, if the aminotransferase elevation is very obvious, further liver ultrasound and other related tests are needed.