Autoimmune hepatitis, AIH, is heterogeneous, or its nature is heterogeneous, as demonstrated by the polymorphism of its clinical course, which can be asymptomatic or insidious, with only mild nonspecific symptoms, such as, malaise, sleepiness, indescribable all discomfort, or similar to acute viral hepatitis, which can manifest as fulminant liver failure, or a significant proportion of insidious cirrhosis, cirrhosis of unknown origin, these unknown causes of liver disease, cirrhosis mostly autoantibody negative. Many acute liver diseases have histological evidence of chronic liver disease and apparently previous liver damage, although the timing is difficult to determine, but generally patients carefully follow the medical history, patients often have “fatty liver”, “unspecified viral hepatitis” “medicated liver” and other past medical history of uncertain cause. The diversity of immunogenetic phenotypes and serologic abnormalities is an important feature of the heterogeneity of AIH, and nowadays the classification into type 1 and type 2 is widely used based on different antibodies. Histological manifestations of AIH are chronic hepatitis, and although some manifestations such as interfaceitis, lymphoplasmacytic infiltration, lymphatic penetration phenomenon, and roseola-like cell hyperplasia are characteristic, there are no specific manifestations of AIH yet, and the diagnosis of AIH must be differentiated from the following diseases. Therefore, for the diagnosis of AIH, two scoring criteria are now proposed by the international community, which have been mentioned in previous articles and will not be repeated.