Whether chemotherapy is needed for early-stage breast cancer depends on the indications, which mainly include axillary lymph node positivity, or lymph node negativity but with high-risk factors for recurrence, etc., and the specifics need to be followed by the doctor. 1. Positive axillary lymph nodes: Adjuvant chemotherapy is generally recommended for those with positive axillary lymph nodes. 2. Negative axillary lymph nodes: Postoperative adjuvant chemotherapy is also recommended for lymph node-negative breast cancer patients with the following high-risk factors for recurrence. High-risk recurrence risk factors include: patient’s age <35 years old, tumor diameter >2cm, tumor grade II-III, choroidal tumor embolus, HER2-positive, ER/PR-negative and so on. In addition to indications, contraindications need to be considered, such as patients in early and middle stages of pregnancy, or patients who are old and frail with severe organic lesions of internal organs, chemotherapy should be carefully selected. Please strictly follow the doctor’s instructions for drug treatment, do not self-medicate.