HPV35 positive indicates a viral infection, the name of the virus is called human papillomavirus infection. HPV35 positive is a high-risk HPV infection, which is related to the occurrence of cervical cancer and requires caution. Therefore, HPV35 positive needs to be further examined by cervical TCT to rule out the presence of cervical epithelial lesions. If there is no epithelial lesion, the problem is not serious and can be reviewed regularly, or treated with vaginal interferon gel or povidon suppositories. If there is any abnormality in TCT, colposcopy and cervical biopsy should be done to rule out any cervical epithelial lesion, and then depending on the degree of cervical epithelial lesion, medication or cervical conization should be done.