Chronic urticaria can cause laryngitis, cardiovascular system diseases, vasculitis, rubella lesions and other secondary diseases. 1. Laryngitis: chronic urticaria secondary bacterial infection can lead to laryngitis, and laryngitis is serious, even suffocation. 2. cardiovascular system diseases: mainly manifested as weakness of the limbs, fever, shortness of breath and other symptoms, some patients will appear myocarditis. 3. Urticaria-like vasculitis: manifested as abdominal pain, diarrhea, vomiting, etc. In severe cases, shock and laryngeal edema may occur and endanger life. 4. Rubella lesions: this lesion is produced more quickly, the local itchy feeling, some patients will also appear systemic symptoms, manifested as loss of appetite, headache. It is recommended that patients with chronic urticaria go to the hospital in a timely manner, and follow the doctor’s instructions to standardize the treatment in order to reduce secondary diseases.