Sartans are best administered according to the patient’s condition. Commonly used drugs include chlorosartan, valsartan, irbesartan, and candesartan. Sartans, also called angiotensin II receptor antagonists, are used to lower blood pressure, treat congestive heart failure, and prevent cardiovascular remodeling. 1. Chlorosartan: clinically used in the treatment of hypertension. It can antagonize the constriction effect of angiotensin II on the renal inlet small arteries and outlet small arteries. It has a protective effect on patients with hypertension and diabetic nephropathy, and can promote uric acid excretion. Adverse reactions are less, some people with dizziness, dry cough and other symptoms after using the drug. 2. Valsartan: the antihypertensive effect can last for 24 hours after taking the drug in patients with essential hypertension, and the main adverse reactions include headache, dizziness and so on. Pregnant and lactating women are prohibited. 3. Irbesartan: the antihypertensive effect can last for more than 24 hours, easily absorbed orally, mainly metabolized by the liver. Used in patients with hypertension combined with diabetic nephropathy, it can reduce proteinuria and increase creatinine clearance. 4. Candesartan: It has the characteristics of potent, long-lasting and high selectivity, and is excreted by kidney and bile, and its long-term application can reduce left ventricular hypertrophy. The above drugs should be consulted with the physician before application, and the medication should be used in accordance with the doctor’s instructions.