Fetal syphilis, also known as congenital syphilis, can be cured by adequate treatment in utero or after birth. Congenital syphilis is due to maternal infection of syphilis, the syphilis spirochete enters the blood of the fetus through the placenta, resulting in the fetus contracting syphilis, which usually develops in the neonatal period, infancy and childhood, and manifests itself in symptoms such as fever, emaciation, jaundice, anemia, hepatomegaly, and so on. During pregnancy, once a pregnant woman is examined for syphilis infection, she needs to be treated with penicillin drugs promptly, which can prevent the fetus from being infected. After the child is born, it can be treated with aqueous penicillin G, benzylpenicillin, procaine penicillin G and other drugs. Ceftriaxone and erythromycin may be used for treatment if necessary. Generally in the uterus or after the birth of active medication, adequate treatment, can be syphilis spirochete removal, to achieve a curative effect. Therefore, it is recommended that patients seek timely medical treatment, early and strictly comply with the medical prescription medication.