There is no exact number or exact rate of how many people have to undergo biopsy after gastroscopy, and the need for biopsy examination can only be decided according to the specific situation of each patient. Gastroscopy is mainly through the gastric tube from the mouth into the stomach and intestines, you can see the tiny lesions in the stomach, so as to make an accurate judgment of the disease, so that doctors can target treatment to ensure the accuracy of medication, if only non-atrophic gastritis, generally do not need a biopsy. If the examination process reveals significant atrophic gastritis, polyps, ulcers or masses in the stomach, a biopsy examination is required. Advantage is also needed to check for the presence of H. pylori through mucosal biopsy and also to check for drug resistance of H. pylori, etc. Mucosal biopsy pathology is a very important test for diagnosing gastrointestinal diseases. Mucosal biopsy is a common adjunct to gastroscopy and is a technique that involves removing diseased tissue from the patient’s body by cutting, clamping or puncturing for pathological examination. The biopsy is the only way to diagnose whether it is malignant or benign. Different lesions have different effects on the patient’s body, so the treatment methods used are also different. If malignant masses can be detected and treated early, a better treatment effect will be achieved, thus preventing continued deterioration of the condition. Most people do not need a biopsy after gastroscopy if it is just an ordinary non-atrophic, but only a few with difficult conditions need a biopsy.