Bead-like nodules are usually the typical pathologic changes of rickets and can usually be diagnosed by imaging features, and the disease is treated by increasing vitamin D intake and raising serum vitamin D levels. Oral vitamin D therapy is currently the mainstay of treatment and should be taken as prescribed after an interview with a physician. Children who have difficulty taking oral vitamin D or whose absorption is impaired by diarrhea may be evaluated by a physician and treated with high-dose burst therapy. Ensure adequate milk intake and timely addition of complementary foods with concomitant nutritional reinforcement. Adhere to outdoor activities in daily life, increase the sunshine time, the average outdoor activity time is not less than 1 hour, pay attention to infants under 6 months to avoid direct exposure to the sun. Rickets can cause acute hypokalemic manifestations in infants and young children, if there are infants and young children with spasms, convulsions, hand and foot spasms, should immediately consult the doctor for calcium supplementation such as calcium gluconate, supplemental vitamin D treatment. Bead-like nodules may also have other causes, such as patients with discomfort, it is recommended to consult a doctor in a timely manner, under the guidance of a professional doctor to clarify the cause of the targeted treatment.