Tobacco and smoke contain many harmful substances that can affect human reproductive and developmental functions. It has been well documented that smoking in women can reduce the probability of conception and lead to placenta praevia, placental abruption, fetal growth restriction, low birth weight and sudden infant death syndrome. Smoking also damages genetic material and can have adverse effects on the endocrine system, tubal function, placental function, immune function, maternal and fetal cardiovascular system, and fetal tissue and organ development. In addition, there is evidence suggesting that smoking can cause ectopic pregnancy and spontaneous abortion. Therefore, it is important for women who are mothers-to-be to quit smoking because smoking can lead not only to reproductive, and developmental abnormalities, but also to the development of malignancies, which have been correlated with laryngeal, gastric, and lung cancers, especially with lung cancer. Smoking can also lead to various respiratory diseases, such as chronic obstructive pulmonary disease, etc. Smoking can also increase the incidence of cardiovascular and cerebrovascular diseases, so it is important to quit smoking.