Losing weight by eating less and not defecating needs to be relieved through lifestyle adjustment, medication and other ways. 1. Lifestyle adjustment: drink more water; increase the amount of food, especially vegetables, fruits and other foods rich in dietary fiber; appropriate exercise can not only relieve constipation, but also help to lose weight; develop a good habit of defecation, regular defecation every day; maintain a happy mood. 2. medication: laxatives can be used to relieve constipation, such as polyethylene glycol, magnesium sulfate, lactulose, keserol, etc.; slow transmission type constipation can also be used to promote gastric power drugs such as mosapride. In daily life, people who need to lose weight should take a healthy way to lose weight, it is not recommended to rely on dieting to lose weight; weight loss to eat less without defecation through lifestyle intervention can not be relieved, it is recommended to go to the hospital, the drug should be used in accordance with the doctor’s instructions.