Whether female patients with multiple myeloma can have cohabitation after autologous stem cell transplantation needs to refer to the patient’s condition, with individual differences, if necessary, you need to consult a professional physician. Multiple myeloma is a kind of malignant hematological disease, because of the abnormal proliferation of plasma cells, the patients can show abnormal increase in serum calcium level, decreased kidney function, anemia, bone pain, etc., and pathological fracture is easy to occur in severe bone destruction. When female multiple myeloma patients receive autologous stem cell transplantation, if they have good recovery, no fever, infection and other rejection reactions, the basic condition of the body is still good, and there is no serious clinical manifestation, they can consider coitus, but they should pay attention to the gentle action to avoid aggravating the burden on the body. If the female patient after transplantation has serious rejection reaction or poor physical foundation condition, such as has developed renal failure, serious bone destruction, etc., coitus is not suitable to avoid causing aggravation of the original condition. After receiving autologous stem cell transplantation, female multiple myeloma patients should pay attention to rest, supplement nutrition, maintain good indoor hygiene to reduce the occurrence of infection and other complications. If there is any special physiological need, the patient should consult the specialized physician in detail, so as to avoid causing adverse consequences and affecting the prognosis.