Systemic lupus erythematosus (SLE) has multiple complications, including hearing and vestibular disorders. Batuecas-Caletrío A, from the Faculty of Medicine of the University of Salamanca, Spain, et al. explored the existence of a subgroup of patients with SLE with widespread inner ear disorders and a potential relationship with migraine. The study found 89 patients with SLE with vestibular symptoms, 50/89 of whom had frequent headaches, 26 of whom met the diagnostic criteria for migraine. 24% of the patients reported sensorineural hearing loss or paroxysmal vertigo. Of the eight (9%) patients with paroxysmal vertigo, one had a definite diagnosis of Ménière’s disease and two others had probable Ménière’s disease. Patients with sensorineural hearing loss were found to have a history of paroxysmal vertigo, but no history of headache or migraine. The results showed that migraine, sensorineural hearing loss and paroxysmal vertigo were coexisting symptoms in patients with SLE, but that sensorineural hearing loss or vertigo were not associated with migraine in these patients. However, sensorineural hearing impairment and vertigo are symptoms associated with SLE patients, suggesting the presence of a common vestibular dysfunction.