Low estradiol at the onset of menstruation is a time when oral estrogenic medications, such as estradiol valerate, can be taken orally as directed. Progesterone can also be added to the second half of the cycle to create a normal artificial treatment that can restore normal menstruation. This is because low estrogen can cause the endothelium to grow at a slower rate, which is not conducive to the implantation of a fertilized egg, and it can also cause the chances of irregular menstruation to occur. At this time through the way of medication can be adjusted, conditioning 3 months or 6 months to stop the drug, as long as the review to return to normal, will not affect the health and reproductive health, do not worry too much, but usually life can eat more soy isoflavones or soy products, because these foods, although there are plants in the estrogen, but for the body is also a very good help.