What should I do if the swollen submandibular lymph nodes don’t go away for more than a year?

Enlargement of submandibular lymph nodes for more than a year does not subside, most considerations related to lymphadenitis, lymphoma, leukemia, etc., can follow the doctor’s prescription of medication or surgical treatment.
1. Lymphadenitis: Lymphadenitis becomes chronic and can last for several years without disappearing. For bacterial infections, antibiotics such as cefadroxil and amoxicillin can be taken as prescribed by doctors; for viral infections, antiviral drugs such as ganciclovir and adenosine monophosphate can be taken as prescribed by doctors. If it develops into lymph node abscess, it can be treated by puncture and suction, incision and drainage.
2. Malignant diseases: mostly caused by lymphoma or leukemia. Radiotherapy and chemotherapy are the main treatments. Commonly used chemotherapeutic drugs for lymphoma include doxorubicin and vincristine.
Leukemia can be treated with targeted drugs such as imatinib mesylate, nilotinib, and rituximab immunotherapy as prescribed by doctors. Leukemia patients should also cooperate with doctors to use cyclophosphamide, methotrexate and other drugs for chemotherapy, radiation therapy, hematopoietic stem cell transplantation and so on.
Submandibular lymph node enlargement for more than a year does not subside, may also be caused by other diseases. You should consult a doctor in time for examination, and follow the doctor’s instructions after clarifying the cause of the disease.