Bone pain in the middle of the two breasts, generally common causes are mainly the following situations: First, breast malignant tumors with metastasis of the sternum, at this time will cause bone pain in the middle of the breast. Patients can improve the molybdenum target or magnetic resonance examination of the breast, clear the nature of the lesion, as soon as possible after the modified radical treatment of breast cancer plus lymph node dissection. After surgery, combine with local radiotherapy and systemic chemotherapy to kill cancer cells as much as possible and prolong patient’s life. Secondly, the patient’s accidental fall may cause fracture of sternum. It manifests as pain in the sternum in the middle of both breasts, at this time, the patient will have difficulty in breathing and activity limitation, and the X-ray or CT examination of the sternum can be perfected. After the nature of the fracture is clarified, surgery should be performed as soon as possible for internal fixation to restore the continuity of the sternum. Symptomatic and analgesic treatment can improve the pain symptoms of the sternum.