Sperm deformity rate of 99% indicates that the sperm deformity rate is too high, which may be caused by environmental factors, androgen deficiency, varicocele, infectious diseases of the reproductive system, etc. Different causative factors lead to different treatments, including detachment from harmful environments, medication, surgical treatments and so on. 1. Environmental factors: For example, prolonged exposure to radiation or toxic substances can lead to high sperm deformity rate. After diagnosis, the surrounding environment should be improved, avoiding exposure to toxic substances and not being in a radiation environment for a long time. 2. Androgen deficiency: For high sperm abnormality rate caused by androgen deficiency, after diagnosis, androgen supplementation drugs should be used to regulate, such as testosterone undecanoate capsule, and reasonable diet, more physical exercise, to improve their physical condition. 3. Varicose veins: For the high sperm abnormality rate caused by varicose veins, which indicates that the varicose veins are more serious, surgical treatment can be considered, such as laparoscopic high spermatic vein ligation. 4. Reproductive system infections: such as prostatitis or seminal vesiculitis, after diagnosis, antibacterial drugs should be used for treatment, such as amoxicillin, levofloxacin, etc., to control the infection in a timely manner and eliminate the infectious factors. In the process of treatment, we must follow the doctor’s instructions, rational use of medication, and to do a good job of daily care, regular medical review.