Chronic superficial gastritis with erosion plus duodenitis is mainly treated with general treatment and medication. 1. General treatment: pay attention to adjust the diet, avoid eating spicy and stimulating food, avoid drinking strong tea, alcoholism and so on. 2. Drug treatment: If there is no H. pylori infection, mainly take acid-suppressing drugs, gastric power-promoting drugs and mucosal protectants, acid-suppressing drugs include omeprazole, rabeprazole, etc., gastric power-promoting drugs include mosapride, domperidone, etc., and mucosal protectants include aluminum thioglycollate, bismuth potassium citrate, etc. If H. pylori infection is present, eradication therapy is required. A quadruple therapy is usually adopted, including a proton pump inhibitor (e.g., omeprazole), a bismuth agent (e.g., bismuth potassium citrate), and two antibiotic drugs (e.g., amoxicillin, metronidazole), and so on. When using the drug, pay attention to the drug components of the allergy is prohibited, the use of drugs must be guided by a doctor, the patient can not be arbitrary use of drugs on their own.