One year old baby woke up crying several times in the middle of the night, may be physiological phenomenon, or child-type intussusception, rickets and other diseases. 1. Physiological phenomenon: one-year-old baby temporarily will not be complete through the language to express their own demands, therefore, when the baby is hungry at night or need to change the diaper will be expressed through the way of crying, so the one-year-old baby woke up several times in the middle of the night crying may be a physiological phenomenon, parents do not need to worry too much. 2. Childhood type intussusception: this disease mostly belongs to primary intussusception, which may be caused by intestinal peristaltic rhythm disorder, only 10% of the cases are caused by infections, intestinal developmental abnormalities and other reasons. Because this disease can cause paroxysmal abdominal pain, so one-year-old children will wake up several times in the middle of the night crying. 3. Rickets: The common cause of this disease is vitamin D deficiency, which is related to lack of sun exposure and insufficient vitamin D intake or synthesis. Generally there are no typical symptoms in the early stage, with the development of the disease, the child will appear night terrors, night crying and other symptoms, can be manifested in the middle of the night waking up several times crying. A one-year-old baby woke up several times in the middle of the night crying, there may be other causes, it is recommended to go to the hospital in time to improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.