H. pylori (HP) test methods: 1, mucosal tissue staining Gastric mucosa tissue section, detection of Hp positive rate, positive indicates the presence of UP in the gastric mucosa. 2, urease rapid test The gastric mucosa biopsy into the urea solution with the indicator phenol red, if there is Hp in the gastric mucosa, the urease secreted by HP decompose urea and produce ammonia, the latter makes phenol red turn red, this method is simple, positive then the initial determination of Hp in the gastric mucosa, but need other methods to confirm. 3, serum Hp antibody assay is an indirect method to check Hp infection, positive indicates that the subject is infected with Hp, but does not indicate that Hp is still present, and is most suitable for epidemiological investigation. 4, urea breath test is a non-invasive diagnostic method, oral administration of 13C or 14C-labeled urea, hydrolyzed to 13C02 or 14C02 by urease produced by Hp on the gastric mucosa and excreted from the lungs, positive indicates current Hp infection, the results are accurate. Treatment of Helicobacter pylori (HP) Proton pump inhibitor (PPI) triplet (PPI + two antibiotics) 7-day therapy and ranitidine bismuth borate (RBC) triplet, (RBC + two antibiotics) are recommended as the preferred first-line treatment regimen, with antibiotics including amoxicillin (A), clarithromycin (C), metronidazole (M), tetracycline (T) and furazolidone (F). PPI+M+C(A) is considered first when the resistance rate of metronidazole is ≤40%; PPI+C+A(M) is considered first when the resistance rate of clarithromycin is ≤15%-20%.