For H. pylori Hp, is it necessary to sterilize? While many patients and even many doctors (including some gastroenterologists) are hesitant about the necessity and benefits of sterilization, Dr. Wei, based on his personal clinical experience, has been emphasizing and calling for the importance of sterilization for several years now. Through authoritative magazines, newspapers, radio stations, and this website, Dr. Wei has published numerous scientific and professional articles to raise awareness of the dangers of Hp among his patients. Recently we have seen the most authoritative voice in the academic world: to sum up: if you have Hp infection, you must kill it if you can! It is not enough to recognize the importance of sterilization, we witness many patients every day in the clinic, and spend a lot of energy and financial resources, but the result is a failure of sterilization! Here, in addition to individual patients because of bacterial mutations, particularly resistant, the vast majority are using the sterilization program is relatively old. For example, clarithromycin, which is preferred in classical bactericidal regimens, is actually highly resistant in many areas of China. Our team, along with TCM treatment, will choose a safer and more effective 4-part bactericidal regimen for Hp-positive regimens with very low drug resistance. The success rate of Hp sterilization is greatly improved. Finding a good protocol can buy time and opportunity for gastric disease treatment. Because once sterilization fails, there is a 3-month interval before re-sterilization in order to protect the liver and restore bacterial susceptibility to the drug.