Gastric cancer metastasis to liver can be treated by surgery, chemotherapy, radiotherapy, targeted therapy and other methods, and comprehensive treatment measures can be taken so as to prolong patients’ life time. The metastatic route of gastric cancer is usually dominated by lymph node metastasis, and most of the patients with progressive gastric cancer can have lymph node metastasis, while a few of them can have blood line metastasis, which is usually to the liver. Once diagnosed with liver metastasis of gastric cancer, patients should take timely surgical treatment. For patients with no contraindication to surgery, radical resection can be performed for primary lesion and metastatic lesion. If metastases are formed locally in liver and rupture occurs, interventional embolization surgery or resection of metastatic foci can be adopted. If the onset of gastric cancer liver metastasis is slow, the situation is calm, or if the patient is unable to undergo surgery, comprehensive treatment such as chemotherapy, radiotherapy and targeted therapy can be adopted to control the metastatic cancer cells, so as to control the development of the disease, prolong the life span and improve the quality of life. Once liver metastasis of gastric cancer occurs, patients should go to regular hospitals in time and cooperate with doctors to take relevant treatment measures, so as to avoid delaying the condition.