Human papillomavirus (HPV) is a human papillomavirus, for women who are sexually active, cervical cancer screening, such as cervical liquid-based cytology and HPV examination, should be conducted before HPV vaccination, except for HPV infection; for women who are not yet sexually active, generally there is no need to do any examination. Since the HPV vaccine is a preventive vaccine, if the examination reveals that a woman is co-infected with HPV, she needs to follow the doctor’s instructions to use interferon and other agents to regulate the local immunity and clear up the viral infection, and then receive the vaccine after turning negative, so as to avoid affecting the effect of the vaccine or further aggravating the disease. Before vaccination, women should also pay attention to the best to avoid menstruation, do not take anti-inflammatory drugs, non-steroidal anti-inflammatory drugs and other drugs. After vaccination, there will be slight pain or redness and swelling and other discomforts, usually about 3 days can improve by itself. For women who want to receive the HPV vaccine, it is recommended that they make an appointment through the regular channels, and consult a professional doctor for details.