The specific manifestations of lumbar spine pain caused by different diseases are different, generally there are deep pain in the lumbar region, localized pressure pain, activity limitation or pain aggravation after activity and other symptoms. 1. Degenerative diseases of lumbar spine: commonly seen in lumbar disc herniation, spinal stenosis, vertebral body slippage and other diseases, there are often deep pain in the lumbar region, localized pressure and pain, activity restriction and other symptoms, the pain will be aggravated by prolonged sitting or bending over for a long period of time, and the symptoms can often be improved after rest or physical therapy. 2. Lumbar spine fracture: lumbar spine pain caused by lumbar spine fracture due to external force, usually the pain is more intense, the position is not fixed, and the patient loses the ability to move immediately after the injury. 3. Lumbar spine tumor or metastatic tumor: lumbar spine pain caused by lumbar spine tumor or metastatic tumor is mainly at night, and can be radiated to one or both sides of the sacroiliac bone, perineum and other parts of the body, which is difficult to be relieved by rest or physical therapy or common painkillers. It is recommended to consult a doctor in time for lumbar spine pain, clarify the cause of the disease with the help of a doctor, and carry out targeted treatment or therapy.