Dydrogesterone is a progestin, 48 years old taking dydrogesterone tablets stopping without menstruation may be due to pregnancy, ovarian hypoplasia, endometrial damage and other conditions, need to be specifically analyzed. 1. pregnancy: if a 48-year-old woman is pregnant after intercourse, there will be no more process of estrogen and progesterone decline in the body, and eating divalproex plays a role in preserving the fetus, so it will not come to menstruation. 2. Low ovarian function: due to low ovarian function, the secretion of estrogen and progesterone is reduced, and dydrogesterone can only supplement endogenous progesterone, so it may not work after stopping the drug, and will not have menstruation. 3. Endometrial damage: If the endometrial lining of the uterus is very thin or there are adhesions, multiple abortions, scraping, hysteroscopic surgery, endometrial adhesions, after stopping the drug, may not have menstruation. Women may experience adverse reactions such as breast pain and migraine headaches during the administration of Deferiprone. The drug is contraindicated in patients who are allergic to the ingredients of the product, have severe liver dysfunction, and have progesterone-dependent tumors. If during the use of the drug there is a severe headache, the appearance of severe hepatic impairment, the drug should be stopped immediately. If the situation of 48 years old taking dydrogesterone tablets stopping without menstruation occurs, it is recommended to consult a doctor in time, under the guidance of the doctor, improve the relevant examination, clarify the cause of the disease, and symptomatic treatment.