There are two main causes of pain in the thumb of the foot. First, painful sensations occur due to strains or strains in the muscles, tendons, ligaments and other soft tissues in the location of the thumb, mostly due to strenuous exercise and collisions with external forces, which form sterile inflammatory lesions and inflammatory metabolites that stimulate the peripheral nerves around them. In addition, when performing activities, these lesions will be further stimulated, resulting in increased pain symptoms. Secondly, gout, a painful sensation is evident in the first metatarsophalangeal joint area, which is mainly due to problems in purine metabolism, resulting in a gradual rise in uric acid, which can form gout, and some patients can develop gout stones in this location, which manifest as redness, swelling and pain. The effect is not obvious after rest treatment, and it is usually necessary to take oral colchicine and anti-uric acid drugs such as propoxur to get effective relief.