After glioma surgery, patients with irritable moods should be analyzed for their condition and treated with sedative medications under the guidance of a doctor. The location of glioma appearing may be in the frontal lobe, cerebellum and other parts of the body, affecting the body’s mental activity, can appear irritable and other emotions, after the tumor is removed after surgery should be sedative drug therapy, such as the use of sodium phenobarbital, olanzapine and other anti-epileptic, to improve the psychiatric symptoms, inhibition of central nervous system, and to control the patient’s irritable mood. It should also timely review CT or nuclear magnetic, except intracranial hemorrhage, cerebral edema and other conditions. In addition to medication, family members should do a good job of monitoring to avoid over-excited behavior such as falling out of bed and self-injury. If the patient has more obvious abnormal movements, the doctor should be informed in time.