Patients are generally used for the treatment of end-stage liver disease, and the cost of liver replacement should be relatively expensive and unaffordable for the average family. The overall cost is significantly higher in economically developed tertiary hospitals, where various tests are done to determine the final type of liver replacement, and the overall cost is generally around 1 million. This of course includes some of the anti-rejection treatment, as well as the post-operative period which may involve the patient taking anti-rejection drugs. In provinces outside of the economically developed world, this type of surgery can only be performed outside of tertiary hospitals, and the overall cost is slightly lower, with a price point that may be around 600,000. Therefore, the overall cost of liver replacement is expensive and should be screened in relation to the patient’s family situation as well as their condition to truly make it affordable for the patient.