Clinically, excessive y-aminobutyric acid is generally indicative of hepatic encephalopathy, and it is found only in neural tissue at levels of 0.1 to 0.6 mg (per gram of brain tissue). y-Aminobutyric acid is a central nervous system inhibitory transmitter, and its elevation is most often seen in patients with acute and chronic hepatic failure. When the metabolizing ability of the patient’s liver is significantly weakened, y-aminobutyric acid bypasses the liver and enters directly into the blood circulation, resulting in a significant elevation of y-aminobutyric acid in the blood. At the same time, it has an effect on the permeability of the blood-brain barrier, causing nerve conduction inhibition, resulting in varying degrees of impaired consciousness. When y-aminobutyric acid is greater than the normal value, the original disease should be actively treated, can be under the guidance of the doctor to protect the liver treatment, such as the use of diammonium glycyrrhizinate, glutathione tablets, etc..