Meniere’s disease is an inner ear disease with idiopathic membranous vagal fluid accumulation, manifested by recurrent episodes of rotational vertigo, fluctuating sensorineural hearing loss, tinnitus and/or a feeling of fullness in the ear. Diagnosis is based on: 1. Episodes of vertigo 2 or more times, lasting from 20 min to several hours. It is often accompanied by autonomic dysfunction and balance disorders. No loss of consciousness; 2. Fluctuating hearing loss, mostly low-frequency hearing loss in the early stage, gradually worsening as the disease progresses. At least one pure tone audiometry for sensorineural hearing loss, auditory reverberation may occur; 3. With tinnitus and/or ear fullness; 4. May have spontaneous nystagmus; 5. Exclude vertigo caused by other diseases, such as benign paroxysmal positional vertigo, vaginitis, vestibular neuritis, drug intoxication vertigo, sudden deafness, inadequate blood supply to the vertebral basilar artery and intracranial occupying lesions. Clinical stages: Early stage: normal intermittent hearing or mild low-frequency hearing loss; Middle stage: hearing loss in both low and high frequencies in the intermittent period; Late stage: full-frequency hearing loss up to moderately severe or more, without hearing fluctuations. Suspicious diagnosis (Meniere’s disease pending): 1. only 1 episode of vertigo with pure tone audiometry of sensorineural hearing loss with tinnitus and fullness in the ear; 2. 2 or more episodes of vertigo lasting 20 minutes to several hours. Hearing is normal without tinnitus and fullness; 3. Fluctuating low-frequency sensorineural hearing loss. Resonance phenomenon may occur. No obvious vertigo attacks. Those meeting any of the above can be considered as suspicious diagnosis.