Severe nasal congestion needs to identify the cause, may be caused by upper respiratory tract infection, allergic rhinitis, nasal septum deviation, etc., need to be under the guidance of the doctor to carry out targeted treatment, may involve drugs such as pseudoephedrine hydrochloride, cetirizine. However, there is no so-called “fast cure” medicine, should follow the doctor’s instructions to standardize the use of drugs and treatment. 1. Upper respiratory tract infection: mainly caused by viral or bacterial infection. With nasal congestion, nasal mucosal congestion, edema, sore throat and other symptoms, can be applied to contain pseudoephedrine hydrochloride and other selective constriction of mucosal blood vessels of the upper respiratory tract of the drug orally. 2. Allergic rhinitis: allergic inflammation of the nasal mucosa caused by specific allergens, mainly manifested as nasal congestion, runny nose, itchy nose. It can be accompanied by headache, dizziness and so on. Oral antihistamines such as cetirizine and loratadine can be taken. 3. Deviated nasal septum: This disease requires surgical treatment, and there is no specific drug treatment. In addition to the above factors, other factors can not be ruled out. It is recommended that patients consult a doctor in a timely manner to clarify the cause of the disease, and then give targeted treatment, do not blindly self-medication.