Floating thumb is a relatively rare congenital hand deformity, but in recent years there has been a significant increase in the trend, and many families are concerned about whether floating thumb is hereditary and whether their second child or baby’s offspring will be affected? Can floating thumb be prevented? We understand the parents’ feelings, but don’t worry too much, we are not sure whether floating thumb is hereditary or not. The cause is more likely to be a malformation of the thumb that is affected to some degree during embryonic development. The teratogenic factors include nutritional deficiencies, fetal neurogenic damage, maternal viral infections, the effects of drugs (especially the sedative thalidomide) and hypoxia. If parents want to prevent floating thumb, they should pay more attention during pregnancy preparation and throughout pregnancy, avoid maternal illness or swallowing some drugs, stay away from second-hand smoke, formaldehyde and other harmful substances, and try to maintain a happy and healthy state of mind and body, which can significantly reduce the chances of having a floating thumb baby. If the baby still appears to have a floating thumb, parents do not have to be too anxious, as it is now possible to preserve the child’s five fingers through surgery the day after, and the post-operative shape and function can be significantly improved.