Patients with hypertension combined with nephropathy prefer to use the antihypertensive drugs of the pulley class. If the blood pressure cannot be reduced smoothly with the pulley class antihypertensive drugs alone, the antihypertensive drugs of the nifedipine or amlodipine class can also be added. If the patient has swelling of the lower extremities or dyspnea on exertion, a small amount of diuretics, such as furosemide, spironolactone or hydrochlorothiazide, should be added. Once a patient with hypertension develops nephropathy, suggesting unsatisfactory control of previous blood pressure, it is important to promptly control blood pressure below 130/80 mmHg, adjust previous antihypertensive drugs, and require a low protein diet to prevent an increase in urinary protein.