The left testicle is enlarged after 1 day of playing the bottle has no effect to consider and testicular inflammation, syringomyelia, testicular torsion, testicular cancer and so on, the patient should follow the doctor’s instructions to use medication, surgical treatment. 1. Testicular inflammation: patients with testicular inflammation can follow the doctor’s instructions to apply antimicrobial drugs such as ofloxacin, cefixime, penicillin and other antibacterial drugs, but also can be used locally 50% magnesium sulfate solution wet compresses, to relieve testicular swelling. Patients in bed rest, can be appropriate to support the affected side of the scrotum. 2. Syringomyelia: usually asymptomatic, small amount of fluid can be followed up. If the condition is serious, the patient should follow the doctor’s instruction to perform surgery such as syringomyelia windowing, syringomyelia reversal, syringomyelia folding and other surgical treatments, and the general effect of drug treatment is not ideal. 3. Testicular torsion: clear testicular torsion needs to be restored as soon as possible, mainly by testicular restoration and fixation, medication can not achieve the purpose of cure. Some testicular torsion patients can also cooperate with doctors to carry out manipulation restoration treatment, and after restoration, surgery should be arranged as soon as possible. Reset is only to buy time for surgery. 4. Testicular cancer: it belongs to malignant tumor, and there may be no effect after 1 day of infusion treatment. Patients diagnosed with testicular cancer should cooperate with doctors to undergo radical orchiectomy, retroperitoneal lymph node dissection and other surgical treatments, and can also cooperate with radiation therapy and chemotherapy after surgery. It is suggested that those who have swollen left testicle and have no effect after 1 day of injection should go to the doctor for further examination so as to clarify the cause of the disease and then follow the doctor’s prescription for treatment, and should not blindly use medicine or traditional Chinese medicine.