Aseptic chronic prostatitis is clinically known as chronic non-bacterial prostatitis or chronic pelvic pain syndrome, and is divided into inflammatory and non-inflammatory subtypes. Inflammatory chronic non-bacterial prostatitis is recommended to be treated empirically with antibiotics, while non-inflammatory antibiotics are not generally recommended. 1. Inflammatory chronic non-bacterial prostatitis: Inflammatory chronic non-bacterial prostatitis is recommended to be treated with antibiotics first, preferred oral ciprofloxacin or other broad-spectrum antibiotics, according to the therapeutic effect and then decide whether to continue to use the drug; such as the presence of chlamydia, mycoplasma and other infections, but also oral azithromycin, clarithromycin, and other antibiotics. 2. non-inflammatory chronic non-bacterial prostatitis: this kind of prostatitis patients do not recommend the use of antibiotics, recommended the use of α-blocker-based treatment, such as alfuzosin, tamsulosin, and so on, in addition to the use of indomethacin, celecoxib and other drugs for anti-inflammatory analgesia, auxiliary treatment of the disease, but do not recommend a large number of long-term use of drugs. The etiology of chronic non-bacterial prostatitis is complex, and its pathogenesis has not yet been fully elucidated, so there is no clear treatment plan, mainly empirical treatment, individuals should not abuse drugs, medication should be strictly in accordance with the doctor’s instructions.