Early stage vitiligo may show negative results under Wood’s lamp, or it may appear as bluish or bright blue-white white patches. Wood’s lamp is an auxiliary examination method based on the fluorescence reaction of the white spots to the Wood’s lamp, which helps in the diagnosis of vitiligo and other skin diseases by checking the fluorescence reaction of the white spots. Vitiligo is a kind of intractable skin disease with pigment loss as the typical manifestation. There are no typical clinical symptoms in the early stage, and there may be mild hypopigmented patches, which are light white or grayish-white, and the border is unclear. Wood’s lamp examination may be negative results, or may be blue-white or bright blue-white white spots and other positive manifestations, need to be combined with the shape of the white spots, clinical manifestations, medical history and laboratory tests and other comprehensive judgment. When patients have expanding or increasing white patches on the skin, or when abnormalities are detected under Wood’s lamp examination, they should consult a doctor in time, and be judged by the doctor according to their specific conditions. Once the diagnosis is confirmed, standardized treatment should be strictly complied with the doctor’s instructions.