Deep venipuncture, also known as central venipuncture, usually refers to the puncture of the subclavian, internal jugular and femoral veins and is mainly used for the treatment of diseases such as peripheral venipuncture when it is difficult to puncture the peripheral veins and when hemodialysis, plasma exchange or hemoperfusion is used to relieve drug intoxication, deep venipuncture and cannulation must be used. If large doses of drugs are applied at the same time and require rehydration and volume expansion, deep venous cannulation must also be used. This technique is also often used when highly nutritious food is given in the gastrointestinal tract for a long period of time, most commonly within the emergency EICU and ICU, where hypertonic drugs are applied and rehydration is required for volume expansion, but some diseases cannot be applied, such as extensive thrombosis of the superior vena cava system, those who are prone to serious local infections, and those who are restless and unable to cooperate cannot be subjected to deep venous The deep venous cannulation should not be used in some diseases, such as extensive thrombosis of the superior vena cava system, severe local infection, restlessness, or inability to cooperate.