TB drugs are anti-tuberculosis (TB) medications, and the correct way to take oral TB drugs is usually once a day on an empty stomach, which is generally the best way to administer them. Currently, the first-line anti-tuberculosis drugs used in clinical practice are rifampicin, isoniazid, pyrazinamide and ethambutol. The correct way to take anti-tuberculosis drugs is to take the daily dose of the drug at the same time, and the combination of drugs in one dose is currently an important treatment for TB. However, patients who are difficult to tolerate the gastrointestinal irritation caused by the drug can take the drug at night before bedtime. Adverse reactions: rifampicin causes adverse reactions mainly in various gastrointestinal symptoms; isoniazid can cause hepatic impairment, peripheral neuritis side effects; pyrazinamide caused by adverse reactions are mainly liver damage; ethambutol caused by the most common adverse reactions are gastrointestinal symptoms. Contraindications: It must be contraindicated in people who are allergic to any of the ingredients contained in the anti-tuberculosis drug used. Precautions: Individuals with some adverse drug reactions to medication should contact their doctor in time and use the appropriate method of treatment under the guidance of the physician. The application of anti-tuberculosis drugs need to do strictly follow the doctor’s instructions, can not be abused, and can not stop the drug.