When you have a cauliflower-shaped swelling on your glans, there are several conditions that are generally considered: the first and most common condition is condyloma acuminata. Warts are caused by human papilloma virus, also called HPV virus infection, and can be single or multiple. It is a good idea to have a good look at the actual website. If you touch it with your hand, it can feel prickly, and the larger ones can be lobulated. Cut a piece and send it to pathology, it can be confirmed. The second common disease is penile cancer and glans cancer. In this case, the cauliflower-shaped bump is darker and more brittle, and bleeds easily when touched, often accompanied by general weakness and anemia. The diagnosis also requires a piece to be taken and sent to the pathology department for testing.