Fetoprotein 15000 cannot be used as a reference standard for survival rate, and it is necessary to improve relevant examinations to make a comprehensive judgment on the stage of the tumor and the degree of malignancy. If the alpha-fetoprotein is 15000, liver cancer should be considered, and liver function tests and related imaging tests, such as ultrasound, CT, etc., and liver artery imaging can be performed if necessary. Patients diagnosed with hepatocellular carcinoma have poor effect of radiotherapy as hepatocellular carcinoma is insensitive to both radiotherapy and chemotherapy. Early stage liver cancer can be treated by surgery to prolong the survival period, if it is advanced liver cancer with portal vein metastasis, clinically it can be prolonged by interventional therapy and other palliative treatments, and liver cancer needs to be supplemented with nutrients, and liver protection treatment at the same time. Early symptoms of liver cancer are not obvious, so it is necessary to have regular medical checkups, raise the awareness of prevention, and actively cooperate with doctors to carry out relevant examinations.