Right subcostal pressure pain usually has the following systemic causes: first, digestive system diseases, the most common factor is cholecystitis, in addition gallstones, biliary obstruction, purulent cholangitis, biliary tract diseases can cause right subcostal pressure pain. Second, diseases of the liver system, such as acute hepatitis, acute cirrhosis, and infectious liver disease can also cause right-sided subcostal pressure pain. Third, appendicitis, peritonitis, gastroenteritis, and intestinal perforation can also cause right-sided subcostal pressure pain. Fourth, circulatory system diseases, such as acute pericarditis and myocarditis, can also cause pain on the right side under pressure. Fifth, respiratory system diseases, the pain of right subcostal pressure is often associated with right-sided pleurisy, right-sided pneumothorax, right-sided pleural effusion, etc.