It is possible to use moisturizing moisturizer after rubbing adapalene gel, but you need to interval 10-20 minutes time, so as not to affect the drug absorption. 1. The main ingredient of Adapalene Gel is Adapalene, which belongs to the class of retinoids. It is suitable for mild to moderate common acne with papules, pimples or pustules as the main symptoms, and it can alleviate the inflammatory reaction mediated by cellular response, thus improving the symptoms related to acne. 2. Adapalene Gel overdose, the local may have obvious redness, peeling or discomfort, at this time, need to use a certain amount of topical moisturizing emollient cream, can be a certain degree of relief of the adverse symptoms brought about by dry skin. 3. Due to the low transdermal absorption of adapalene, it is not recommended to use moisturizing cream immediately after rubbing adapalene gel, which may affect the absorption of the drug, and can be spaced out over a period of 10-20 minutes, to be absorbed after the use of moisturizing cream after the absorption of adapalene gel. If you need to use Adapalene Gel to treat acne, it is recommended that you visit a hospital and be evaluated by a doctor, and then use the medication under the doctor’s supervision to avoid delaying or aggravating your condition.