Not all need sedation for pain relief after surgery. Sedation for pain relief after surgery can help patients get through the period of irritability smoothly, which is conducive to the recovery of the condition. Appropriate use of postoperative sedation, such as intravenous analgesic pumps, internal pain relief and sedative drugs, can reduce the patient’s irritability and stabilize the mood, and at the same time can reduce the oxygen consumption of brain cells to prevent cerebral edema or secondary cerebral hemorrhage. After the use of sedative drugs, postoperative patients may experience nausea and vomiting, so in the process of use, health care workers and family members need to closely observe the patient’s condition changes to avoid risks. If irritability occurs, the cause should be found in time to determine whether it is caused by sedation and treated symptomatically. During the recovery period, patients are advised to pay attention to rest, eat some high-quality protein, such as milk, eggs, moderate exercise, which is conducive to the recovery of the wound.