When a child has a fever in the middle of the night, it is necessary to choose the appropriate antipyretic method according to the degree of elevation of the child’s temperature, such as physical hypothermia, oral medication, and so on. It is also important to treat the cause of the fever. For children with fever but body temperature <38.5 ℃ can use warm water on the child's forehead, reduce the wearing of clothing and other physical methods of cooling, encourage children to drink more water, some children's body temperature can gradually decline, for children with body temperature ≥38.5 ℃ need to use antipyretic drugs such as ibuprofen, acetaminophen and other antipyretic treatments under the guidance of a doctor. At the same time, the treatment of the cause of the disease is also very important for the recovery of body temperature. For example, if the respiratory tract infection is caused by bacterial infection, antibacterial drugs such as cefaclor and cefuroxime should be actively used for anti-infection treatment. In case of influenza virus infection, oseltamivir phosphate should be used for treatment. All of the above drugs should be used under the guidance of a doctor, avoid self-medication. It is recommended that children with fever should be seen by a specialist for evaluation and treatment.