Obesity has become a serious health problem, the world is now estimated to have a total of 671 million obese people, more than half live in the United States, China, India, Russia, Brazil, Mexico, Egypt, Germany, Pakistan, etc., and it is expected that the global diabetes population of 205 million people by 2035, and for those who are severely obese almost all of them have gone through the nightmare of dieting to lose weight and exercise to lose weight, and almost all of the of the internists will say to obese patients control your mouth and move your legs. Almost all of them will think: weight gain is because the intake of calories is greater than the consumption, to reduce weight to eat less and exercise more. For obese people, diet and exercise will almost always reduce weight, but almost invariably rebound, so why diet and exercise can not lose weight successfully? The United States of Dr. POKIN and other research found that from 1977 to 2006, the average daily intake of calories per person increased by 570 calories, if calculated in accordance with 1 pound of fat containing 3,500 calories, if each person daily intake of more than 570 calories, the average person should be fatter 476 pounds. Of course our bodies don’t do this, so are these increased calories due to increased consumption as a result of our increased exercise? The truth of course is that from 1997 to 2006, people were exercising less, so if you are consuming so-called calories based on how many calories you take in and then how much exercise you do, then 95.4% of them are failures. 辉县市人民医院普外科张松海When your body needs calories but can’t get them after you exercise and work, etc., it will choose to slow down its metabolism in order to consume less energy instead of going through the complex biochemical reaction of converting fat in the body into energy. So eating less will only be a way for our body to consume less, it won’t help us lose fat. At the same time, after dieting for a long time, the body thinks that famine is coming and will try to accumulate fat, muscle loss, the basal metabolic rate will be slower, so once the diet can not be sustained, even if you just eat the same food as before, the body will think that you have eaten too much, and the extra calories will be converted into fat and stored, and the result is that you are even fatter than before. After a person has recovered from a famine, his body will find ways to store more fat in case of the next famine. The energy burned by exercise is often offset by the consequent increase in calorie intake, and every person’s metabolism has a tuning point, with fast metabolizers having a lower tuning point than slow heart sinking metabolizers. This point does not depend on the amount of calorie intake and consumption. Weight gain is the elevated set point, when the hormones of our metabolism change, the set point of weight rises. Therefore, weight loss is not successful not only because of the lack of willpower of the person, he has a physiological reason, so it is important to eat the right foods and choose the right exercise routine in order to lower the set point and lose weight. For obese patients, almost all have insulin resistance, or hyperinsulinemia, insulin is produced by the pancreas, which determines whether the body stores fat or burns it, and when the blood glucose When it rises, insulin secretion increases for glucose absorption. Too much glucose in the cells is converted to fat, and for obese patients who eat too much, glucose in the blood rises quickly, and the pancreas releases large amounts of insulin, leading to hyperinsulinemia. With too much insulin, the cells don’t burn fat. High insulin, more blood sugar, the role of leptin is also affected, even if the fat is already a lot, the person’s appetite will not be affected, and there is no desire to exercise, so the weight of the regulatory point is raised. The Chinese diet is based on rice, noodles, steamed buns, etc. These foods are converted into calories very efficiently, and will rapidly increase the glucose content of the blood. Of course, the emptying of these foods is also very fast, the feeling of satiety lasts for a short time, the feeling of hunger comes quickly, and looking for food to eat. Some so-called weight loss tips say that sleeping also burns calories for weight loss purposes. Of course, in our human body has a basal metabolic rate, even if lying still will have more than 1,000 calories consumed, exercise, especially treadmill running exercise muscle groups are few, most of the muscles are treated as a liability, so when running, the body will be adapted to the loss of other muscles, so in many people running to adhere to a period of time after they will find that their other muscles wasting away, body fat analysis found that muscle content Therefore, after running for a period of time, many people will find that their other muscles have lost weight, and body fat analysis reveals that their muscle content has decreased and fat content has increased. The loss of muscle represents a decrease in calorie consumption because of muscle depletion. With the increase of age, the human body muscle atrophy, the reduction of activity, more accelerated muscle loss, so after 30 ~ 40 years of age will find that the abdominal muscles gradually disappeared, but the fat layer is thickening. Chinese people have experienced thousands of years of hunger, so there is a “hunger gene” in the Chinese population, which monitors your body’s calorie balance at any time, once there is a breeze, it will increase the absorption of calories and reserves, so in the Western research found that in the United States living in the foreign population, African Americans and Chinese are more likely to be obese, which is related to the imprint of thousands of years of hunger. Thousands of years of hunger stigma is related to the memory of hunger can be passed on to future generations through genes, the hunger gene is not only manifested in the absorption of calories, but also in the intake of caloric deficit will quickly reduce energy consumption, that is, to reduce the basal metabolic rate. Therefore, for Chinese people, eating less sometimes leads to faster obesity and more difficult dietary control. A large number of follow-up studies have shown that for patients with severe obesity, either low-calorie diet or dietary control plus exercise will reduce body weight, but almost all of them will regain weight after 5 years, and as long as they lose weight once, rebound will occur, resulting in the more you lose, the more fat you get. Diet and exercise is ineffective for severe obesity patients to reduce weight, has been released by the American Dietetic Association, for severe obesity patients, weight loss after surgery, will reduce the patient’s calorie regulation point, so that the dietary control is easier, hyperinsulinemia is alleviated. This leads to long-term results in weight control.