Ursodeoxycholic acid is mainly used clinically for the treatment of gallbladder cholesterol stones and cholestatic liver disease, while dehydrocholic acid is mainly used clinically for the treatment of cholelithiasis, chronic cholecystitis, biliary dysfunction, and as an adjunctive therapy for chronic hepatitis. The main pharmacological effect of ursodeoxycholic acid is to reduce the reabsorption of cholesterol in the digestive tract and to decrease the secretion of cholesterol by the bile duct cells, which in turn reduces the proportion of cholesterol in bile and promotes the gradual dissolution of cholesterol stones. Therefore, ursodeoxycholic acid is mainly used for the treatment of gallbladder cholesterol stones and cholestatic liver disease, and can also be used for the treatment of bile reflux gastritis. However, the process of treatment with deoxycholic acid requires the selection of different drug dosages as well as usage according to different diseases, which must be taken under the guidance of professional physicians. The pharmacological effect of dehydrocholic acid is to physiologically stimulate the liver cells to increase hepatic blood flow, the liver cells metabolism is vigorous secretion of more water to dilute the bile, so as to clean the bile ducts, prevention and treatment of cholestasis. Dehydrocholic acid is mainly used for the treatment of cholelithiasis, chronic cholecystitis, biliary tract dysfunction in the clinic, and can also assist in the treatment of chronic liver disease. Although ursodeoxycholic acid and dehydrocholic acid are both drugs for the treatment of gallbladder disease, but the specific mechanism of action is different, there are differences in dosage, you need to choose the right drug under the guidance of a specialist.